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Image Search Results
Journal: PLoS ONE
Article Title: Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects
doi: 10.1371/journal.pone.0113308
Figure Lengend Snippet: (A) and (D): The genomic profile of genes displayed in UCSC (hg19), the genomic locus of target regions in ChIP assay (black block on the gene schematic) and the CpG island (green block underneath the gene schematic) assayed by the MASSARRAY platform are shown. The capital letter beside the block indicates the corresponding panel below. The number beside the block indicates the genomic location that was targeted. In the ChIP assay results (B and E), the enrichment in the y-axis represents the relative enrichment fold in which the higher enrichment in case or in control is designated as 1. C) and F) indicate the DNA methylation level. Notably, in F, the DNA methylation status of KvDMR1 is shown.*: P <0.05; **: P <0.01 (Student's t -test). TSS: transcription start site.
Article Snippet: The Sequenom
Techniques: Blocking Assay, DNA Methylation Assay
Journal: PLoS ONE
Article Title: Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects
doi: 10.1371/journal.pone.0113308
Figure Lengend Snippet: (A) The methylation level of H19 DMR1 is stable in RA-treated mice. For details, see the legend in . (B) and (F): The genomic profile of genes displayed in UCSC (mm9), the genomic locus of target regions in ChIP assay (black block in the gene schematic) (corresponding results shown in C and D or G and H), and the CpG island (green block underneath the gene schematic) (corresponding results shown in E and I) detected by MASSARRAY assay are shown. The number beside the block indicates the genomic location that was targeted. In the ChIP assay results (C and D or G and H), the enrichment in the y-axis represents the relative fold enrichment in which the higher enrichment in case or control is designated as 1. *: P <0.05; **: P <0.01; ***: P <0.0001 (Student's t -test). TSS: transcription start site.
Article Snippet: The Sequenom
Techniques: Methylation, Blocking Assay